Natalie Portman, Kiefer Sutherland, the White Stripes and Dr. Phil McGraw will be among the guest voices on the upcoming season of "The Simpsons."

Joe Mantegna will reprise his role as Springfield's infamous mob boss Fat Tony when the animated Fox show begins its 18th season Sept. 10. Joe Pantoliano and Michael Imperioli guest-star as Fat Tony's main thugs, the network announced Monday.

The White Stripes voice themselves in the Sept. 17 episode when Bart organizes a benefit concert to repair his arm that was mangled by a tiger Lisa rescued from the local pound.

McGraw, Fran Drescher and comedian Richard Lewis guest-star in a Halloween episode on Nov. 5.

Sutherland voices a hard-nosed colonel when Homer lands in basic training on Nov. 12.

Also paying a visit to Springfield will be authors Tom Wolfe, Gore Vidal, Michael Chabon and Jonathan Franzen.

In May, the Emmy-winning series will air its 400th episode.